Researchers of a retrospective cohort study have identified specific risk factors that may increase the likelihood of developing psoriatic arthritis (PsA) in patients with psoriasis. The study, which focused on identifying predictive factors of PsA, found that female patients with psoriasis and severe disease, nail involvement, and those requiring oral systemic therapy are at a greater risk of developing PsA. Recognizing these predictive elements is crucial for informed decision-making in clinical practice, especially since early intervention in PsA is known to lead to better long-term outcomes.
The study involved 330 subjects with psoriasis, 25% of whom later developed PsA. Key findings included the observation that factors such as being female, having severe psoriasis, nail involvement, and prior use of oral systemic treatments significantly increased the risk of developing PsA. The odds ratio for female patients was 3.33, and for those with severe psoriasis, the OR was 27.41. The researchers emphasized the importance of increased screening for PsA in patients with these specific psoriasis characteristics to facilitate earlier diagnosis and treatment. The findings point to the need for more extensive studies to fully understand the predictive factors of PsA, potentially improving patient outcomes through early identification and management.
Reference: Smith T. Female Patients with Psoriasis, Related Clinical Characteristics More Likely to Develop Psoriatic Arthritis. HCPLive. Published February 11, 2024. Accessed March 13, 2024. https://www.hcplive.com/view/female-patients-with-psoriasis-related-clinical-characteristics-more-likely-to-develop-psoriatic-arthritis
