In a recent study, researchers analyzed acetylcholine receptors, mainly the α subunit, and the complement system in myasthenia gravis (MG). They highlight the damaging effects of AChR antibodies through direct blockade and complement activation. The importance of the complement system is also noted, along with the significance of biomarkers for tailored MG treatment and safety concerns, including the risk of meningococcal infections.
Reference: San PP, Jacob S. Role of complement in myasthenia gravis. Front Neurol. 2023 Oct;14:1277596. doi: 10.3389/fneur.2023.1277596.
