Lorazepam is frequently used to mitigate agitation in bipolar 1 mania trials, but it exhibits varying usage patterns in both controlled trials and clinical practice.

Link: https://www.pocn.com/inconsistencies-in-lorazepam-use-for-bipolar-mania/?npi=&utm_medium=email&utm_source=Ongage&utm_content=&utm_campaign=2098014272

Reference: Safer DJ. Lorazepam use during clinical trials of adults with bipolar mania episodes. Contemp Clin Trials Commun. 2023 Apr 7;33:101122. doi: 10.1016/j.conctc.2023.101122. PMID: 37128576; PMCID: PMC10147970.