A recent study explored the link between disturbances in human microbiota and the development and progression of myasthenia gravis (MG). MG patients have distinct microbiota differences in their oral and gut regions compared to healthy individuals. The accepted idea connects MG to the immune-regulating role of microbiota. Changes in certain bacteria can lead to immune system alterations in MG patients, creating an inflammatory environment. Researchers concluded that factors like medication and lifestyle changes in MG patients could indirectly affect these microbial changes, and that further detailed research, especially on oral bacteria and the effects of oral care and diet, is necessary.
Reference: Schirò G, Iacono S, Balistreri CR. The Role of Human Microbiota in Myasthenia Gravis: A Narrative Review. Neurol Int. 2023 Mar 10;15(1):392-404. doi: 10.3390/neurolint15010026. PMID: 36976669; PMCID: PMC10053295.
