Researchers reviewed recent advances in the treatment and diagnosis of hepatic encephalopathy (HE), emphasizing the importance of identifying and treating the underlying causes. The most used pharmacological treatment involves non-absorbable antibiotics and non-absorbable disaccharides; other agents, such as branched-chain amino acids, probiotics, alternative antibiotics, or intravenous L-ornithine L-aspartate, are available, but their efficacy is still a subject of debate. The researchers highlight the need for further research.
Reference: Nardelli S, Gioia S, Faccioli J, et al. Hepatic encephalopathy – recent advances in treatment and diagnosis. Expert Rev Gastroenterol Hepatol. 2023 Mar;17(3):225-235. doi: 10.1080/17474124.2023.2183386. Epub 2023 Feb 26. PMID: 36843291.
