Antimicrobial resistance is a major global health threat. Researchers discuss novel sequencing-based approaches for identifying antibiotic resistance genes (ARGs), and while numerous different gut microbes encode for ARGs, they aren’t uniformly distributed across or transmitted by various members of the microbiome. Evidence for the role of commensal gut microbes in encoding antimicrobial resistance genes is assessed, as is the degree to which they are shared both with other commensals and with pathogens, and the host and environmental factors that can impact resistome dynamics.
Reference: Crits-Christoph A, Hallowell HA, Koutouvalis K, Suez J. Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome.it al. 2022 Jan-Dec;14(1):2055944. doi: 10.1080/19490976.2022.2055944. PMID: 35332832; PMCID: PMC8959533.
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