Evidence suggests that there may be differences in disease burden and treatment response between sexes in psoriatic arthritis (PsA). While PsA is equally prevalent in males and females, studies have shown that females experience a higher burden of disease. However, few studies have specifically investigated the differences in psoriasis and its impact on disease burden between sexes in patients with PsA.
Researchers of this study assessed the differences and similarities between sexes in two groups of patients with PsA. The findings revealed that while psoriasis was more prevalent in males, it had a worse impact on disease burden in females. Female patients with PsA showed higher disease activity, worse function, and greater disease burden. The study suggests the need for further research on this topic with larger population studies to better understand and address these differences between sexes in PsA.
Reference: Lubrano E, Scriffignano S, Fatica M, et al. Psoriatic Arthritis in Males and Females: Differences and Similarities. Rheumatol Ther. 2023;10(3):589-599. doi:10.1007/s40744-023-00535-3
Link: https://link.springer.com/article/10.1007/s40744-023-00535-3
