Data presented at Digestive Disease Week 2024 indicates that patients with inflammatory bowel disease (IBD), particularly Crohn’s Disease (CD), have a significantly increased risk of developing chronic kidney disease (CKD). An analysis of nearly 15,000 patients from a tertiary referral center over 12 years revealed that CKD was approximately three times more common among patients with CD than those with ulcerative colitis. Notably, 11% of patients with CD required kidney transplantation.
Among the patients with CD, those with a history of kidney stones were eight times more likely to develop CKD, and those with three or more surgeries had six times the odds of CKD. Conversely, current immunomodulatory use was associated with a 78% lower risk of CKD development. The researchers emphasized the importance of monitoring renal function in patients with CD and addressing renal calculi to mitigate CKD risk. These findings highlight the need for targeted approaches to improve prevention and treatment outcomes for CKD in patients with IBD.
Reference: Iapoce C. Diagnosis of Crohn’s Disease Linked to Chronic Kidney Disease Risk. HCPLive. Published May 18, 2024. Accessed June 23, 2024. https://www.hcplive.com/view/diagnosis-crohns-disease-linked-chronic-kidney-disease-risk
Link: https://www.hcplive.com/view/diagnosis-crohns-disease-linked-chronic-kidney-disease-risk
