Researchers investigated compression therapy’s effects on psoriatic plaques in 30 patients with lower-leg edema. For four weeks, one leg received compression therapy alongside standard care, while the other didn’t. Results showed minor improvements in severity and pain in the treated leg, with no Koebner phenomenon occurrence. Although it didn’t significantly enhance psoriatic plaques, compression therapy didn’t worsen the condition, suggesting its safe application in psoriasis patients with edema, considering basic contraindications.

Reference: Krefting F, Hölsken S, Moelleken M, Dissemond J, et al. Randomized clinical trial of compression therapy of the lower legs in patients with psoriasis. Dermatologie (Heidelb). 2023 Aug;74(8):605-613. German. doi: 10.1007/s00105-023-05155-0. Epub 2023 May 9. PMID: 37160420; PMCID: PMC10366302.

Link: https://pubmed.ncbi.nlm.nih.gov/37160420/