Hypertension is highly prevalent among patients with obstructive sleep apnea (OSA), but blood pressure (BP) control varies and may be influenced by comorbid insomnia. Researchers of a study explored the relationship between insomnia symptoms and uncontrolled BP, as well as resistant hypertension (RH), in 326 patients with OSA. Among participants included in the analysis, 64.1% had uncontrolled blood pressure and 15.6% had resistant hypertension. Greater severity of obstructive sleep apnea was linked to an increased likelihood of resistant hypertension (OR, 2.92; 95% CI, 1.71-4.99). After adjusting for various factors, such as demographic characteristics, sedative hypnotics usage, sleepiness, OSA severity, and quality of life, individuals with insomnia symptoms had three times higher odds of developing resistant hypertension. Insomnia was associated with an increased likelihood of RH in patients with OSA, however, there was no association between insomnia and uncontrolled blood pressure.
Reference: Wu H, Guo Y. Risk of resistant hypertension associated with insomnia in patients with obstructive sleep apnea. Sleep Med. 2023;101:445-451. doi:10.1016/j.sleep.2022.12.001
Link: https://www.sciencedirect.com/science/article/abs/pii/S1389945722012503
